Thermo Scientific NanoDrop Eight Spectrophotometer

NanoDrop Eight UV-Vis Micro volume Spectrophotometer allows molecular biologists to measure the concentrations and purity of their biological samples, identify and correct for contaminants, and differentiate between DNA and RNA.

The Thermo Scientific NanoDrop Eight Spectrophotometer simultaneously evaluates eight samples in 20 seconds or less, enabling academic and industrial researchers to analyze protein and nucleic acid samples more quickly and efficiently. The instrument can also measure high-concentration samples of up to 200 absorbance units without dilution, saving users the time-consuming, error-prone task.

You can confidently quantify your samples with the NanoDrop Eight multichannel spectrophotometer from Paracor Medical. This is a next-generation NanoDrop multichannel instrument with improved hardware and the best software features of the Thermo Scientific NanoDrop One/OneC spectrophotometer.

NanoDrop Eight Spectrophotometer features:

The NanoDrop Eight Spectrophotometer shares standard features with our flagship NanoDrop One/One^C Microvolume UV-Vis Spectrophotometer:

NanoDrop Eight Spectrophotometer Improvements

• Wider dynamic range – measure higher concentration samples without dilution – up to 10,000 ng/µl dsDNA or 145 mg/ml IgG
• Auto-Measure and Auto-Blank Functions – Multiple sample handling can be simplified thanks to instantaneous measurements when the pedestal arm is lowered. These features can be turned on or off.
• Ergonomic Dispensing Without Offset – The pedestal is perpendicular to the front of the instrument, creating a natural dispensing movement for users; The pipette guide is magnetic and movable from side to side, allowing left and right-handed users to dispense samples quickly and conveniently.

Nucleic Acid

• Perfect for high throughput UV-Vis spectroscopy. Quantify as little as 1 ul sample
• Measure up to 8 samples at a time
• Broad dynamic range (2 – 10,000 ng/ul dsDNA) means no need to dilute your samples.
• Automatic calculation of sample concentration and purity ratios for dsDNA, ssDNA, and RNA samples
• Spectral scans provide information about potential contaminants and help to improve overall sample quality.
• Acclaro sample intelligence technology identifies and corrects for common contaminants (protein, guanidine salts, and phenol)
• Mammalian DNA/RNA differentiation with concentration correction

Proteins

• This 8-channel spectrophotometer can quantify as little as 2 ul of your protein samples.
• Protein A280 module for accurate quantification of purified proteins
• Coefficients stored for common protein standards or enter your own
• Broad dynamic range (0.06 – 300 mg/ml BSA) removes the need for dilutions
• Identify and correct for nucleic acid contamination in your purified protein samples using chemometrics
• UV-Vis module allows A205 measurements to be carried out for peptides or proteins lacking tryptophan or tyrosine residues

Data Handling

• PC controlled system
• Utilize Windows logins for access control
• Customize user preferences and data handling for individual users
• Import sample ID lists, manually name samples using a keyboard or use barcodes
• Format data exports to include absorbance data, report data or both
• Export data in a range of formats, including .csv and .tsv
• Data formats compatible with leading LIMS platforms for easy integration
• Set a directory for data export, and then get your LIMS to sweep this folder for archiving
• Optional SciVault software allows compliance with 21 CFR part 11
• Install SciVault onto a central computer to control privileges and view audit logs across multiple NanoDrop Eight instruments in different labs

Find out the true concentration of your nucleic acids or protein without interfering with sample contaminants. Understanding the composition of a sample helps you perform subsequent experiments the first time.

• Contaminant Identification – Recognizes common contaminants in nucleic acid and protein samples that may inhibit subsequent reactions or falsely increase calculated concentrations.
• Correction of calculations – application of chemometric algorithms to determine the true concentration of the analyte without taking into account the pollutant
• Differentiate DNA from RNA – Algorithms can identify mammalian RNA contaminating a dsDNA sample or mammalian dsDNA contaminating an RNA sample.

SciVault software for NanoDrop spectrophotometers aids regulatory compliance.

Reference Library

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